Scar Removal
In human beings and domestic pets, scarring in the skin after trauma, surgery, burns or a sports injury is an important health problem, usually resulting in altered aesthetics, loss of function, restriction of tissue movement and/or growth and adverse psychological effects.
Modern treatments are strictly empirical, troublesome and unpredictable. There are no prescription medicines for the prevention or treatment of dermal scarring. Skin wounds on early mammalian embryos heal flawlessly with no scars, whereas wounds to adult mammals are prone to scarring.
In scar treatment research, specialists are exploring the cellular and molecular differences between scar-free healing in embryonic wounds and scar-forming healing in adult wounds. Relevant differences include the inflammatory reaction, which in embryonic wounds consists of fewer numbers of less differentiated inflammatory cells. This occurrence, along with augmented levels of morphogenetic molecules implicated in skin growth and morphogenesis, implies that the growth factor profile of an embryonic injury is very different from that of an adult injury.
These experiments resulted in scar-less healing in the adult subject and have lead to the identification of appropriate therapeutic targets. It has been found that effective skin care markedly improves or completely avoids scarring during adult injury healing in experimental animals. Some of these new drugs have successfully completed safety and other tests, such that they have entered human medical trials with approval from the appropriate regulatory authorities. Based on auspicious results from such volunteer studies, the leading drugs have now entered human patient-based tests e.g. in skin graft donor sites.
The theory is that evolutionary pressures have been exerted on medium sized, widespread, dirty wounds with considerable tissue damage e.g. bites, bruises and contusions. Modern wounds (e.g. resulting from trauma or surgery) caused by sharp objects, are recent occurrences not previously found in nature, in which the evolutionary selected wound healing responses are somewhat useless. It has been demonstrated that both repair with scarring and regeneration can occur within the same animal, including man, and of course within the same tissue, thereby implying that they share similar mechanisms and regulators.
Consequently, by slightly altering the ratio of growth factors present during adult wound healing, we can induce adult wounds to heal flawlessly with no scars, with accelerated healing and with no adverse effects, e.g. on wound strength or wound infection rates. This implies that scarring may no longer be an unavoidable sequel of modem injury or surgery, and that a fully new pharmaceutical concept to the prevention of human scarring is now possible. Not only skin suffers from scarring; they can appear in many other tissues as well.
Thus scar-improving drugs could have extensive benefits and prevent complications in various tissues, e.g. the prevention of blindness after scarring due to eye injury, support of neuronal reconnections in the peripheral and central nervous system by the avoidance of glial scarring, restitution of normal gut and reproductive function by avoiding strictures and adhesions after injury to the gastrointestinal or reproductive systems, and the recovery of locomotor function by avoiding scarring in tendons and ligaments.
Scars caused by injuries, burns or surgeries can now be quickly eliminated. This exclusive formula is an all-natural scar treatment that will get the job done.
Published December 19th, 2007
Filed in Health
